Nutrients, herbs & natural products studied for Endometriosis
14 PubMed clinical trials & meta-analyses analyzed
AI summary
Evidence stage: Human Clinical TrialThe abstracts describe several nutrients, plant-derived products, and a probiotic studied in relation to dysmenorrhea and endometriosis-related symptoms. Most human evidence is from randomized controlled trials in primary dysmenorrhea, including chamomile plus 1-theanine beverage, turmeric, cinnamon, oleoylethanolamide, juniper berry, dried figs, and vitamin B1, with reported changes in pain and symptom scores. For endometriosis specifically, the abstracts include a pilot randomized trial of the probiotic Ligilactobacillus salivarius CECT 30632 and trials of add-back regimens containing sex steroids, which are not grouped as natural products here because they are drugs/hormones rather than nutrients or herbal products. Overall, the strongest evidence in this set is human clinical trial evidence, but it is condition-specific mainly to primary dysmenorrhea rather than endometriosis. This evidence is educational; it is not FDA-approved and is not medical advice.
Doses are those reported in the studies, not recommendations. Talk to your doctor before taking anything.
Ligilactobacillus salivarius CECT 30632
ProbioticLimited evidenceHuman Clinical TrialDoses studied: Oral administration; exact dose not specified in abstract
Duration: Not specified in abstract
In a pilot randomized, double-blind, placebo-controlled trial in women with endometriosis, the probiotic was studied alongside standard dienogest treatment. Vaginal microbial diversity stayed unchanged between groups, but about 20% of participants showed individualized microbiota shifts, IL-10 levels decreased in 65% of probiotic-supplemented participants, and serum oestradiol levels were reported to be significantly reduced by about 50% in the probiotic group.
Sheng-Hua-Tang
HerbLimited evidenceHuman Clinical TrialDoses studied: 200 mg/kg orally in mice
Duration: Seven consecutive days in mice; clinical trial duration one week
This abstract reported experimental transcriptomic effects in mice and a pilot randomized, open-label clinical trial in postpartum women. The database analysis noted use in menstrual disorders, especially dysmenorrhea, and the clinical trial reported alleviation of uterine contraction pain and breast swelling pain after one week; the abstract does not provide endometriosis-specific outcomes.
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