Nutrients, herbs & natural products studied for Psoriasis
14 PubMed clinical trials & meta-analyses analyzed
AI summary
Evidence stage: Meta-AnalysisAcross the abstracts, the studied non-drug nutritional and natural products for psoriasis included a synbiotic, nicotinamide riboside, and aloe vera, while several reviews also mentioned dietary patterns and specific dietary components such as probiotic, prebiotic, n-3 fatty acid, and dietary fiber content. Most of the directly studied agents were evaluated in human clinical trials, with outcomes focused on psoriasis severity scores, patient-reported outcomes, or laboratory measures such as serum trace elements. Aloe vera was mentioned in a dermatology review as having been studied in psoriasis, but the abstract does not provide psoriasis-specific trial details. Vitamin D-related compounds, urea, and topical combination products were also studied, but they are not all natural products and many abstracts focus on comparative topical therapy rather than nutrient supplementation. This evidence is educational; it is not FDA-approved and is not medical advice.
Doses are those reported in the studies, not recommendations. Talk to your doctor before taking anything.
Nicotinamide riboside
NutrientModerate evidenceHuman Clinical TrialDoses studied: Oral NR 500 mg twice daily
Duration: 4 weeks
In a randomized, placebo-controlled study in mild-to-moderate psoriasis, oral nicotinamide riboside was associated with reduced Th17 immune responsiveness. The abstract reports increased circulating SLIT2 levels and enhanced SLIT2 production in dermal fibroblasts, with downstream findings consistent with reduced canonical Th17 polarization and fibroblast inflammatory activation.
Lactocare® synbiotic
ProbioticLimited evidenceHuman Clinical TrialDoses studied: Two times daily; exact formulation dose not specified in abstract
Duration: 12 weeks
In a randomized, double-blind, placebo-controlled clinical trial in mild to moderate psoriasis, Lactocare® was studied for effects on serum electrolytes and trace elements. The abstract reports measurement of Zn, Cu, Mg, Na, Fe, P, Ca, and K at baseline and week 12, but the provided text does not include the study's outcome direction for the intervention group.
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